Studies on Structure-Activity Relation-ships of Guanidine Derivatives. II. : Actions of Aminoethyl-guanidine Derivatives in Adrenergic Mechanisms
نویسندگان
چکیده
منابع مشابه
The Antiviral Action of Polyhexamethylene Guanidine Derivatives
Although the PHMG (polyhexamethylene guanidine) and other oligomer guanidines are known as highly efficient biocides against a broad spectrum of microorganisms and eukaryotic cells, the cell protection by PHMG derivatives has been established firstly in this study. The antiviral protection was also exhibited after 15 min pretreatment of different cell cultures with low-concentration of PHMG sal...
متن کاملThe histochemical recognition of certain guanidine derivatives.
AKAGUCHI'S test for arginine depends on the production of a pink or red colour when certain guanidine derivatives are treated with a-naphthol and sodium hypochlorite in alkaline solution (Sakaguchi, 1925). This test had been familiar to biochemists for 19 years before it was independently adapted to histochemical use in the same year by Serra (1944) and myself (1944). Our results were published...
متن کاملEndplate channel block by guanidine derivatives
The effects of the n-alkyl derivatives of guanidine on the frog neuromuscular junction were studied using the two-microelectrode voltage clamp and other electrophysiological techniques. Methyl-, ethyl-, and propylguanidine stimulated the nerve-evoked release of transmitter. However, amyl-and octylguanidine had no apparent presynaptic action. All of the derivatives blocked the postsynaptic respo...
متن کاملThe Structure of the Guanidine-II Riboswitch
The guanidine-II (mini-ykkC) riboswitch is the smallest of the guanidine-responsive riboswitches, comprising two stem loops of similar sequence. We have solved high-resolution crystal structures of both stem loops for the riboswitch from Gloeobacter violaceus. The stem loops have a strong propensity to dimerize by intimate loop-loop interaction. The dimerization creates specific binding pockets...
متن کاملAntimicrobial activities of amine- and guanidine-functionalized cholic acid derivatives.
Compounds in a series of cholic acid derivatives, designed to mimic the activities of polymyxin B and its derivatives, act as both potent antibiotics and effective permeabilizers of the outer membranes of gram-negative bacteria. Some of these compounds rival polymyxin B in antibacterial activity against gram-negative bacteria and are also very active against gram-positive organisms. Other compo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1966
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.86.9_802